Protesting crowds, however, were modest in number throughout the weekend compared with the more charged protests of the first three nights.
The demonstrations follow a grand jury`s declining to file charges against a white police officer for placing an unarmed black man in a fatal choke-hold, a banned police maneuver.
Dozens of protesters converged on Grand Central Terminal in midtown Manhattan, carrying signs that read "Police brutality is a deadly force," "Against state tyranny" and "I can`t breathe."
The last of these slogans were the last words of 43-year-old Eric Garner, an asthmatic who died July 17 after being placed in a choke-hold by Officer Daniel Pantaleo of the New York Police Department.
Once inside the main concourse of the station, they staged a die-in, a form of civil disobedience where demonstrators lie down in a public space and remain still, as if dead.
They continued their march through the 42nd street before entering and again holding a die-in at the H&M retail clothing store in Times Square, a famous square formed by the intersection of Seventh Avenue, 42nd Street and Broadway.
Another group of demonstrators also laid down at the Pennsylvania Station, the city`s main intercity train station, and in a Macy`s department store near Union Square, about 2 miles south of Times Square.
Demonstrations also erupted in other U.S. cities including Chicago, Philadelphia, Miami, Minneapolis and Seattle.
More demonstrations are expected on Monday in New York City, with some protest groups reportedly planning a demonstration at the Barclays Center.
Britain`s Prince William and his wife Kate, who are on a three-day visit to the city, are scheduled to watch the Brooklyn Nets-Cleveland Cavaliers basketball match at the center.
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