The impact of climate change was less severe in London, where 64 out of 315 deaths were blamed on manmade effects.
Scientists arrived at the figures after combining climate model simulations of the 2003 heatwave with a health impact assessment.
They found that human-induced climate change increased the risk of heat-related deaths by about 70% in central Paris and 20% in London.
The study, published in the journal Environmental Research Letters, looked at the three summer months from June to August.
Lead researcher Dr Daniel Mitchell, from Oxford University, said: “It is often difficult to understand the implications of a planet that is 1C warmer than pre-industrial levels in the global average, but we are now at the stage where we can identify the cost to our health of manmade global warming.
“This research reveals that in two cities alone hundreds of deaths can be attributed to much higher temperatures resulting from human-induced climate change.”
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