The unveiling of the Ronaldo statue led many on social media to question the work's resemblance to the player.
It was revealed at a ceremony to name the island's airport after him.
"It is impossible to please the Greeks and Trojans. Neither did Jesus please everyone," Mr Santos said.
He said that his creation was "not as simple as it seems" to produce, adding that it took him 15 days to complete and that the finished item "was a matter of taste", the Guardian newspaper reports.
The bust by Emanuel Santos, unveiled at Cristiano Ronaldo Airport in Funchal
"Cristiano saw the photos that his brother sent him," Mr Santos told broadcaster Globo.
"I was with his brother at Cristiano's museum in Madeira and from the messages he sent, I could tell that he liked what he saw," he said.
Mr Santos said that Ronaldo had asked him to make minor changes in order to make the player look younger.
"He only asked for some wrinkles that gave him a certain expression in his face when he's about to laugh to be changed," he said.
On Wednesday, Mr Santos told Portuguese TV channel RTP that he had not yet had the opportunity to talk to Ronaldo personally since the unveiling, but said that he would "reach out to him to know his feedback".
"It's always a great honour to work on project like that," he said.
However, shortly after the sculpture was revealed on Wednesday, it was mocked on the social media site Twitter.
"They got the Adams Apple [sic] and the hair right. That's something," wrote Ryan Post. "Creepy!" added Mel Bishop.
Some even suggested that the sculpture looks more like the former Republic of Ireland captain Niall Quinn.
Portuguese President Rebelo de Sousa said Ronaldo "projects Madeira and Portugal across the world far more than anybody else".
The 32-year-old forward is a local hero in Madeira, where he is seen as a rags-to-riches success. He already has a museum about him in his hometown of Funchal.
The player later said on Twitter: "Happy and honoured to have my name given to the Madeira airport!"
Ronaldo is not the first footballer to have an airport named after him. Belfast airport was named after former Manchester United player George Best in 2006, a year after he died.
Portugal's president and the prime minister flew to Madeira to unveil the tribute.
The sculpture will remain on permanent display outside the terminal entrance.
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