The charges brought by Special Counsel Robert Mueller are seen as a major development in his continuing probe into the US 2016 election.
President Trump has said the indictment shows his campaign did "nothing wrong".
The Russian foreign minister was being questioned by participants at the Munich Security Conference.
Asked about the charges, he said that even Vice-President Mike Pence had called the investigation into question.
"So until we see the facts, everything else is just blather."
But Mr Trump's National Security Adviser, H R McMaster, said evidence of Russian meddling was "now incontrovertible".
It would become harder to conceal attempts to "interfere in our democratic process", he added.
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